Grasp the EpiPen in a fist and press the black, rounded tip hard into the thigh. The syringe is overfilled; more than half of the solution remains in the syringe after use and CANNOT BE REUSED. The Certa Dose ® epinephrine 1 mg/mL IM/SC syringe is FDA-cleared. Holding by the finger grips, and while in a seated position, face the needle downward and slowly insert the needle into the thigh. Slowly inject the syringe into the thigh while sitting down. All rights reserved. Push until it clicks. An epinephrine autoinjector (or adrenaline autoinjector) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. You can inject insulin into your abdomen, outer upper arm, buttocks, hip, and the front and side of the thigh. Only a healthcare provider should give additional doses of epinephrine if you need more than 2 injections for a single anaphylaxis episode. Copyright © 2021 IBM Watson Health. Needle insertion site anesthesia (eg, topical freezing spray and/or injectable 1% lidocaine without epinephrine, in a 3-mL syringe) Optional: For therapeutic injection, 5- to 10-mL syringe with 2 to 3 mL 1% lidocaine without epinephrine , rarely with injectable depot corticosteroid (eg, … Each SYMJEPI (epinephrine injection, USP) syringe contains 0.8 mL of sterile aqueous solution of epinephrine for intramuscular or subcutaneous administration. Discard needle properly in sharps container if additional needles are available. You may repeat the injection every 5 to 10 minutes as needed. Do not remove the blue safety release (EpiPen® or EpiPen Jr®), the gray end caps (Adrenaclick®), or the red safety guard (Auvi-Q®) on the autoinjector until you are ready to use it. All rights reserved. Do not use this medicine if the liquid has changed its color (pinkish or brown in color), has become cloudy, or if there are particles in it. Hold it there for 10 seconds to ensure a full dose. If you use the Symjepi® prefilled syringe: Do not remove the needle cap until you are ready to use it. Do not place patient information or any other foreign objects in the carrier case with the prefilled syringe, as this may prevent you from removing the prefilled syringe for use. However, this tube or case is not waterproof. Do not throw it away in the trash bin. Epinephrine is a natural hormone and neurotransmitter that occurs in the human body. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This may activate the device by accident (a "click is heard, the orange needle is extended, and the window is blocked), making it unusable in case of an emergency. are breastfeeding or plan to breastfeed. However, that may not always be possible, so creating an Anaphylaxis Action Plan and staying organized is the best way to prepare for a potential emergency. Where do I inject insulin? This pre-filled syringe is latex-free, sterile, and comes in a LifeShield™ Abboject™ glass syringe. If not, retain needle with syringe and remaining epinephrine as additional doses may be required. Hold for 2 seconds. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. If the person has a heart problem, do not inject more than 2 times in one visit. It is not known if epinephrine will harm your unborn baby. For example, if you're supposed to give yourself 3 cc of a drug, you would want to use a syringe that holds precisely 3 cc (or just a little more). ©2020 USWM, LLC. This content does not have an Arabic version. 2006-09-01 00:00:00 An elderly male patient was admitted to the ICU after successful resuscitation from a cardiac arrest on the general ward. 4. Alpha- and Beta-Adrenergic Agonist Epinephrine 0.1 mg / mL Injection Pre-filled Syringe 10 mL This product is a prescription drug. However, the dose is usually not more than 0.3 mg per injection. Inject the Epinephrine . This content does not have an English version. Don’t forget to slide it up to cover the needle before putting the used SYMJEPI device back in its case. An epinephrine autoinjector (or adrenaline autoinjector) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It should be clear and colorless. 8. Remove the syringe and massage the injection area for 10 seconds. Do not inject into a vein or the buttocks. Do not put your thumb, fingers, or hand over the black base (Auvi-Q®), orange (EpiPen® or EpiPen Jr®), or red (Adrenaclick®) tip of the autoinjector or over the needle of the Symjepi® prefilled syringe. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Epinephrine is a natural hormone and neurotransmitter that occurs in the human body. You should not use the autoinjector if the expiration date has passed. Inject the syringe into the outer thigh and fully push the plunger. Do not reuse the remaining portion of the medicine that is left in the autoinjector, prefilled syringe, or vial. This fills the syringe with air. And search more of iStock's library of royalty-free stock images that features Adrenaline photos available for quick and easy download. Use second syringe if necessary. Also, it is best not to use an anesthetic with epinephrine on persons with heart problems. Adults and children weighing 30 kilograms (kg) or more—0.3 to 0.5 milligram (mg) injected under the skin or into the muscle of your thigh. Children weighing less than 30 kg—Dose is based on body weight and must be determined by your doctor. This medicine comes with patient information and instructions leaflet. Despite using considerable pressure and attaching the syringe to various ports and then a peripheral line, we could not inject the epinephrine. You can give the injection through clothes or on bare skin. Image of allergic, auto, medicine - 182262397 6. For more information, ask your healthcare provider or pharmacist. Adrenaclick®, Auvi-q®, Epipen®, Epipen JR®, Twinject®: Adults and children weighing 30 kilograms (kg) or more—0.3 milligram (mg) injected under the skin or into the muscle of your thigh. You may need a second SYMJEPI syringe if symptoms continue or recur. SYMJEPI is a simple device that allows you to inject epinephrine into the middle of the outer thigh when an allergic emergency occurs. If your dose is less than 30 units, use a 3/10 mL syringe. If more than 2 injections are needed for 1 reaction, however, those should be given only under medical supervision. Drs. Do not inject this medicine into a vein, into the muscle of your buttocks, or into your fingers, toes, hands, or feet. A few ampules of epinephrine and some syringes can be purchased from most pharmacies for around $20. Ask your doctor or pharmacist if you have any questions. Children weighing less than 7.5 kg—Use and dose must be determined by your doctor. The information contained in this section is intended for US healthcare professionals only. SYMJEPI is indicated in the emergency treatment of allergic reactions (Type 1) including anaphylaxis to stinging insects (e.g., order Hymenoptera, which include bees, wasps, hornets, yellow jackets and fire ants) and biting insects (e.g., triatoma, mosquitoes), allergen immunotherapy, foods, drugs, diagnostic testing substances (e.g., radiocontrast media) and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis. Anxiety and discomfort related to the need to self-inject epinephrine contributes to food-allergic adolescents’ occasional failure to carry or use an autoinjector, a problem associated with fatalities. (Ropivacaine, Epinephrine, Clonidine, and Ketorolac) 50 mL in Sodium Chloride 60 mL Syringe R.E.C.K. It is most often used for the treatment of anaphylaxis.The first epinephrine autoinjector was brought to market in 1983. When ready to use SYMJEPI, pull cap off to expose needle. All rights reserved. If you are using this medicine at home, make sure you or any of your family members understand exactly how to give them. If you are using the epinephrine injection in a child, make sure to hold his leg firmly in place and limit movement before and during an injection. Before using SYMJEPI, please familiarize yourself with the steps to giving an injection or watch the SYMJEPI instructional video . The EpiPen autoinjector has become hard to afford recently. This medicine comes with an autoinjector trainer and a separate trainer instructions for use. Check the injection kits regularly to make sure that the liquid has not changed its color. Epinephrine injection is used for emergency treatment of severe allergic reactions (including anaphylaxis) to insect bites or stings, medicines, foods, or other substances. If the insulin is injected into the muscle, it gets absorbed into the blood stream too fast. The Commissioner of Health has approved the addition of Syringe Epinephrine and at the request of the SEMAC, this approval includes the intramuscular administration of 1:1000 epinephrine using a 1cc syringe, a 23 gauge, 1 inch intramuscular safety needle and a single dose 1:1000 epinephrine packaged in a 1mg/ml vial as an addition to the scope of practice for an EMT. Be safe The best defense against anaphylaxis is to avoid what you are allergic to altogether. Do not remove the needle cap until you are ready to use it. Cuts on the skin, bent needles, and needles that remain in the skin after the injection, have happened in young children who do not cooperate and kick or move during the injection. It is most often used for the treatment of anaphylaxis.The first epinephrine autoinjector was brought to market in 1983. Unlike the others, Symjepi is a manual syringe, rather than an autoinjector. Unfortunately, during a stressful emergency situation, this has sometimes led to the erroneous administration of the full 1 mg dose IV, which could prove harmful to some patients. This medicine may be given through clothes if needed. Use lidocaine only, or mepivacaine 3% only. Push the plunger all the way down until you hear a "clicking" sound. The maximum pediatric dose is up to 0.3 mg, that’s 0.3 ml of epinephrine (1:1000). To study the stability and sterility of epinephrine when stored in syringes. As a result, some people are resorting to manual syringes as a cheaper alternative. SYMJEPI™ from Sandoz (a Novartis division) is a portable syringe pre-filled with epinephrine. Be aware 7. Medical Warehouse, Inc. 72 Grays Bridge Road Brookfield, CT 06804 United States of America 800-969-6945 Epinephrine is cheap, and so are syringes. Conveniently, a 10 ml syringe actually holds 11 ml, and a 20 ml syringe holds 22 ml. It comes in a two-pack and is available in 0.15 mg and 0.3 mg. Do not drop the carrier case or SYMJEPI prefilled syringe. Hold it for 2 seconds. If your dose is different, do not change it unless your doctor tells you to do so. EPINEPHrine 0.1 mg/mL in 10 mL syringes have a 3.5 inch needle for intracardiac use, which is not removable and not compatible with needleless tubing/systems. Follow your doctor's orders or the directions on the label. On examination we discovered that the nozzle of the first syringe was … It is designed for health care provider use when administering subcutaneous or intramuscular epinephrine 1 mg/ mL to an adult or pediatric patient in an anaphylactic emergency. iStock Woman Injecting Epinephrine Using Autoinjector Syringe Stock Photo - Download Image Now Download this Woman Injecting Epinephrine Using Autoinjector Syringe photo now. Do not inject this medicine into your buttocks, hands, fingers, toes, or feet. The pen can inject right through clothing. Keep the autoinjector or prefilled syringe in its carrier tube or case to protect from damage. When ready to use SYMJEPI, pull cap off to expose needle.To ensure no accidental epinephrine leakage, do not touch the plunger until the needle is fully inserted. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Before you push the needle under the skin, be sure its pointed end is facing in the correct direction. Ask your healthcare professional how you should dispose of any medicine you do not use. Mayo Clinic does not endorse companies or products. SYMJEPI may cause serious side effects. Tell the healthcare professional that you have given yourself an injection of epinephrine. Inject and hold for as long as you were told. Be sure to practice first with your autoinjector trainer before an allergy emergency happens to make sure you are ready to use the real Auvi-Q®, Adrenaclick®, EpiPen®, or EpiPen Jr® autoinjector in an actual emergency. If you use the Symjepi® prefilled syringe: You may need to use more than one injection if your allergic reaction does not get better after the first shot. Epinephrine can be self-administered from an autoinjector. Adults and children weighing 30 kilograms (kg) or more—0.3 milligrams (mg) injected under the skin or into the muscle of your thigh. This medicine comes in 3 forms:an autoinjector syringe and needle kit, a prefilled syringe, or a vial. Inspect the autoinjector from time to time before needing it to ensure the blue safety release (EpiPen® or EpiPen Jr®) is not raised and that the autoinjector can be easily remove from the carrier tube. The concern with 1 mg ampuls or vials of EPINEPHrine is that the contents must be drawn into a syringe. Nearly 650 agencies participated in a pilot program using the new kits. Ask your healthcare provider to show you how to properly hold the leg of a young child during injection. Do not give into the buttocks. It is also used to treat anaphylaxis caused by unknown substances or triggered by exercise. This site complies with the HONcode standard for trustworthy health information: verify here. Children weighing 15 to 30 kg—0.15 mg injected under the skin or into the muscle of your thigh. Independent and simulated use studies suggest that color-code syringes may significantly reduce critical dosing errors. Get helpSeek medical attention immediately after using SYMJEPI. Children can squirm in these stressful situations. After injecting epinephrine, get medical help right away. SYMJEPI™ pre-filled epinephrine syringe. Click "OK" if you are a healthcare professional. Push the air into the vial. Needle insertion site anesthesia (eg, topical freezing spray and/or injectable 1% lidocaine without epinephrine, in a 3-mL syringe) Optional: For therapeutic injection, 1% lidocaine without epinephrine , with injectable depot corticosteroid (eg, triamcinolone acetate, 20 to 40 mg) Using a syringe epinephrine kit, prepare a correct pediatric dose of epinephrine Deliver an intramuscular injection into a training device. Little is known about the effects on epinephrine when it is drawn up in advance and stored as prefilled syringes. Please see full Prescribing Information for SYMJEPI. The autoinjector needs to stay in place for a minimum of 3 seconds following activation. If no blood, administer 0.3 ml of epinephrine (1/3 of syringe) for any patient. Draw up 0.3 ml of epinephrine 1mg/ml 1:1000, syringe approximately 1/3 full. 1Ready. The syringe is overfilled for stability purposes; more than half of the solution remains in the syringe after use and CANNOT BE REUSED. Hold the EpiPen in place while slowly counting to 10. This … Do not inject into the vein, buttocks, fingers, toes, hands, or feet. If you use a syringe that contains only 2 cc, you would have to inject yourself more than once (which would be unnecessarily painful). Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 5. A SYMJEPI training device that features a fake needle is available for practice. Carry this medicine with you at all times for emergency use in case you have a severe allergic reaction. Each SYMJEPI (epinephrine injection, USP) syringe contains 0.8 mL of sterile aqueous solution of epinephrine for intramuscular or … Each SYMJEPI 0.15 mg pre-filled syringe delivers a single dose of 0.15 mg of epinephrine from epinephrine injection, USP (0.15 mg/0.3 mL). The syringe has visual markings with the standard epinephrine doses in anaphylaxis. More than two sequential doses should only be administered under direct medical supervision. d. Using sterile 3 ml IM syringe, remove needle protector from syringe e. Draw plunger back to 1ml (cc) mark (syringe now contains 1ml of air) f. Pierce the center of the stopper of the vial containing the diluting solution with the needle of the syringe g. Turn the vial upside down and inject the 1 ml of air from the syringe into the vial h. Do not flip the blue safety release off using the thumb or by pulling it sideways, or by bending and twisting it. Watch the training video for Teva's epinephrine auto-injector. 10. SYMJEPI features a safety guard to keep you protected. Blocked epinephrine syringe Blocked epinephrine syringe Srivastava, D.; Ghori, A.; Brennan, K.; Coventry, J. Throw away expired, unwanted, or unused EpiPen® or EpiPen Jr® in an FDA-cleared sharps container. With the cap still on, pull back the plunger to the line on your syringe for your dose. This medicine is injected into the muscle of your outer thigh only. This will reduce the risk of an injection-related injury. Do not remove the needle cap until you are ready to use it. Get emergency medical help now. Push the needle end (orange end of the autoinjector) firmly against the outer thigh until it "clicks". Other Epinephrine Options. Do not touch or bend the needle. Holding by the finger grips, and while in a seated position, face the needle downward and slowly insert the needle into the thigh. Drug information provided by: IBM Micromedex. Following the lead of King County, Washington, Cushman and his team designed a standard syringe with special markings for adult and child doses of epinephrine, and worked with a manufacturer to assemble a kit with the syringe, medication, alcohol pads, etc. See how to give a SYMJEPI injection in this short video. Get Help. Children weighing less than 15 kg—Use and dose must be determined by your doctor. You should get emergency medical care right away after using SYMJEPI. are pregnant or plan to become pregnant. King County Washington EMS system, which uses the “Check and Inject” program, estimates they have saved $335,000 annually by switching to a syringe method. It has a luer lock… If you have any questions about this, check with your doctor. A nurse or other trained health professional will give you this medicine in a medical facility to treat hypotension with septic shock. Especially tell your healthcare provider if you take certain asthma medicines. You may need a second SYMJEPI syringe if symptoms continue or recur. Inject the orange tip of the epinephrine auto-injector firmly into the middle part of the child’s upper thigh. Remove the syringe and massage the injection area for 10 seconds. Photo about Man Injecting Epinephrine Using Auto-injector Syringe As An Emergency Treatment For Allergic Reaction. Store the injection kits at room temperature, away from heat, moisture, and direct light. Call 911 and Discard the EpiPen . Once the injection has been administered, using one hand with your fingers behind the needle, slide the safety guard up until it clicks to cover the needle. Only a healthcare provider should give additional doses of epinephrine if you need more than 2 injections for a single anaphylaxis episode. Unlike EpiPen and Adrenaclick, you must manually inject … In the past, Symjepi was only found in hospitals and clinics, but it is now available in retail pharmacies nationwide. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Epipen Injection Auto Injector Syringe 0.3mg Adult Twin Pack 2/Pk 3451926 | Mylan Specialty LP - 49502050002 Know the medicines you take. Each syringe is labeled with easy to recognize color zones that match the widely adopted color standard pediatric color coding system for weight. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. The correct dose has been injected if the plunger has been pushed all the way down and the solution window is at least partially blocked. Advertising revenue supports our not-for-profit mission. Dispose of the prefilled syringe and carrier case, and replace if damage or leakage is noticed or suspected. Melanie Martinez. Inform patient they are going to receive an injection, side effects may include feeling shaky or heart racing. This contains the correct dose of medicine your doctor has prescribed. Remove needle and carefully re-cap using one-handed technique. The American Academy of Allergy, Asthma & Immunology is a professional organization that regularly publishes updated practice parameters on the treatment of anaphylaxis. The Certa Dose ® epinephrine 1 mg/mL IM/SC syringe is FDA-cleared. “I could make up a kit with a pre-filled syringe for about 35 cents that could have the same effect as a $400 auto-pen,” says Dr. Lanier. Each syringe is labeled with easy to recognize color zones that match the widely adopted color standard pediatric color coding system for weight. To ensure no accidental epinephrine leakage, do not touch the plunger until the needle is fully inserted. Also, tell your doctor if you or your caregiver has severe arthritis of the hands. The Hospira Epinephrine 0.1MG/ML 10ML pre-filled syringe comes in three packaging options: available by a box of 10, or a case of 50. This is to avoid an accidental injection. If you are about to use the autoinjector, pull up straight the blue safety release (EpiPen® or EpiPen Jr®) with one hand and hold the pen with the other hand. Epinephrine is a life-saving drug that treats the symptoms of a severe allergic reaction by stopping the airway from swelling. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 … Tell your healthcare provider of all known allergies. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Each SYMJEPI (epinephrine injection, USP) syringe contains 0.8 mL of sterile aqueous solution of epinephrine for intramuscular or subcutaneous administration. The autoinjector trainer has a grey color (for Auvi-Q®, EpiPen® or EpiPen Jr®) or beige color (for Adrenaclick®) and does not contain any medicine or needle. An injection of synthetic epinephrine through a spring-loaded syringe can act as … Children weighing 7.5 to 15 kg—0.1 mg injected under the skin or into the muscle of your thigh. Use this medicine only as directed by your doctor. Read and follow these instructions carefully. Throw away the autoinjector, prefilled syringe, or vial after you have used it. Clip 5-3 How and why to buffer lidocaine with epinephrine. No, manually drawing epinephrine from a vial or ampule into a syringe and then administering is NOT the same as using an autoinjector. Epinephrine auto-injectors are the preferred method of epinephrine administration, but are not universally available or affordable. Slowly inject the syringe into the thigh while sitting down. The dose of this medicine will be different for different patients. Do not store the medicine in the refrigerator or freezer, or into your vehicle's glove box. This might seem complicated, and indeed, it does take longer to deliver the product than with an autoinjector like the Epipen unless you keep some small syringes prefilled with the medication. Before using SYMJEPI, tell your healthcare provider about all of your medical conditions, including if you: have heart problems or high blood pressure. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. The needle cap on the SYMJEPI prefilled syringe helps to prevent needle sticks and accidental injection of epinephrine. These are not all the possible side effects of SYMJEPI. Melanie Martinez. Remove the syringe and massage the area for 10 seconds. SYMJEPI may affect the way other medicines work, and other medicines may affect how SYMJEPI works. 1, 2. Click here to view Indication and full Important Safety Information, For any supply questions, please call 1-800-230-3935. Place a tourniquet above the injection site and, after IM epinephrine is administered, inject up to 0.1 mL of epinephrine into the large local reaction site to slow absorption. Read it again each time you refill your prescription in case there is new information. Symjepi, a prefilled syringe of epinephrine used to treat anaphylaxis, is another option available during the EpiPen shortage. Epinephrine is a lifesaving medication in the treatment of anaphylaxis. Glass vials of epinephrine with needles/syringes may be in emergency kits as seen on airplanes. Inject the medicine into the fleshy outer portion of the thigh. You may need a second SYMJEPI injection if symptoms continue or recur. You may need to use a second SYMJEPI (epinephrine) injection if symptoms continue or recur. *Patent Pending Otherwise, please include your State License number in the comments section of the order. Inject insulin into the fat layer just under your skin. It is not known if epinephrine passes into your breast milk. According to a recent survey, 13 states have training programs to allow BLS to inject epinephrine and 7 others are considering it. There is also a new pre-filled syringe device that you can use to inject epinephrine. SYMJEPI is a registered trademark of Adamis Pharmaceuticals Corporation. Push the plunger all the way down until you hear a "clicking" sound. To report SUSPECTED ADVERSE REACTIONS, contact Adamis Pharmaceuticals Corporation at 1-800-230-3935 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. If your State License number is on file we can ship this item to you. Get Help. Best practice for treating anaphylaxis is to administer epinephrine via an epinephrine auto-injector, according to HealthFirst Medical Advisory Board Member Dr. Stanley Malamed and the American Dental Association (ADA).However, some times you may need to know how to administer an epinephrine injection from an ampule or vial. in Sodium Chloride solution for injection To place an order today, please speak to your Hospital Account Manager or contact Customer Service at: 888.339.0874 or Customer.Service@QuVaPharma.com 0620A R.E.C.K. USWMSYMJ-00075 10/20. On the other hand, if you use a syringe that holds 15 cc, it will be harder to see the cc markings and measure 3 cc accurately. Do not use the autoinjector or prefilled syringe if the liquid is discolored or cloudy, or if there are particles in it. IMPORTANT NOTE: SYMJEPI should ONLY be injected into the middle of the outer thigh. The dose is 0.01 mg per kg of body weight injected under the skin or into the muscle of your thigh. If you use a syringe that contains only 2 cc, you would have to inject yourself more than once (which would be unnecessarily painful). Epinephrine reduces blood flow, and this could damage areas that have small blood vessels, including the hands and feet. If you are using the epinephrine injection in a child, make sure to hold his leg firmly in place and limit movement before and during an injection. feelings of over excitement, nervousness or anxiety. Adverse Reactions The needle cap on the SYMJEPI prefilled syringe helps to prevent needle sticks and accidental injection of epinephrine. You may need further medical attention and may need to use the second device if symptoms continue.*. You may repeat the injection every 5 to 10 minutes as needed. Insert the needle into the rubber top. SYMJEPI can be injected through clothing if necessary. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Portions of this document last updated: Aug. 01, 2020. To do so, may increase the chance of having serious side effects. Keep in mind: Instructions for giving an injection with either SYMJEPI 0.3 mg or SYMJEPI 0.15 mg are exactly the same, so you only need to remember one set of steps. Call your medical provider right away after injection. 1, 2. If the carrier case or prefilled syringe is dropped, check for damage and leakage. An injection of synthetic epinephrine through a spring-loaded syringe can act … Select and cleanse area for subcutaneous injection, primary sites upper arm or thigh. If you accidentally drop it, check for damage or leakage. SYMJEPI and other medicines may affect each other, causing side effects. Do not keep outdated medicine or medicine no longer needed. Pointing syringe up, expel all air. There are other options that do not auto-inject the epinephrine. This signals that the injection has started. Do not remove the needle cap until you are ready to use it. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special - 40% off – Mayo Clinic Diet Online. The following information includes only the average doses of this medicine. Independent and simulated use studies suggest that color-code syringes may significantly reduce critical dosing errors. Go to the emergency room right away if you accidently inject epinephrine into any part of your body other than your thigh. Following the lead of King County, Washington, Cushman and his team designed a standard syringe with special markings for adult and child doses of epinephrine, and worked with a manufacturer to assemble a kit with the syringe, medication, alcohol pads, etc.